Chapter 12 All in the Mind 

Abused children are at least 50% more likely than the general population to suffer from serious depression as adults, and will find it much harder to recover from this illness.  

Adults who were subjected to childhood abuse and neglect are also at significantly higher risk of a range of other conditions including schizophrenia, eating disorders, personality disorders, bipolar disease and generalized anxiety. They are also more likely to abuse drugs or alcohol. 

psychologically damaged by their early experiences. → what are the molecular events that underlies this psychological damage or invoke the soul just as a Freudian therapist may invoke the psyche.  

Mechanistic explanation → is misinterpreted and taken to imply that humans are essentially robots, wired and programmed to respond in certain ways to certain stimuli. → phenomenon can have a mechanistic basis, without being deterministic.  

Our brains contain one hundred billion nerve cells.  Each neuron makes links with ten thousand other neurons to form an incredible three dimensional grid.  

The child is father to the man 

Over expression of cortisol happen? 

Relaxed rats and mellow mice 

Receptor was highly expressed → sensitive → subdue the downstream hormonal pathway through the negative feedback loop  

Silencing the silencer 

Remember, remember